Quinolines and derivatives
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Filtered Search Results
AdipoGen Acridine Orange Sol 2 in H2O
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Chemical. CAS 65-61-2. Formula C17H19N3 . HCl. MW 301.81. Acridine Orange hydrochloride salt is a cell-permeable metachromatic fluorescent dye that stains DNA and RNA. It is used as a nucleic acid-selective fluorescent cationic dye useful for cell cycle determination and staining dead cells. Being cell-permeable, it interacts with DNA and RNA by intercalation or electrostatic attractions respectively. When bound to DNA, it is very similar spectrally to fluorescein, with an excitation maximum at 502nm and an emission maximum at 525nm green. When acridine orange associates with RNA, the excitation maximum shifts to 460nm blue, and the emission maximum shifts to 650nm red. Acridine orange will also enter acidic compartments such as lysosomes where it becomes protonated and sequestered. At low pH inside the organelles, it will emit an orange fluorescence peak at 590nm and for optimal endosome visualization a blue light excitation 475nm is used.
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Apexbio Technology LLC Acridine Orange hydrochloride 65-61-2 50mg
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Acridine Orange hydrochloride (65-61-2) is a small-molecule fluorochrome targeting nucleic acids It is designed to bind double-stranded DNA and single-stranded DNA or RNA thereby enabling differential nucleic acid staining in live cells Acridine Orange hydrochloride exerts its biological activity primarily through selective intercalation with nucleic acids and pH-dependent accumulation in acidic organelles resulting in green fluorescence for dsDNA and red/orange fluorescence for ssDNA/RNA In cell-based assays Acridine Orange hydrochloride exhibits cytotoxicity with reported IC50 values typically ranging from 0 5 5 M Based on these pharmacological properties Acridine Orange hydrochloride holds research potential in apoptosis detection assessment of lysosomal integrity and function and antitumor activity studies
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TARGETMOL CHEMICALS INC MEPACRINE 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Mepacrine (Erion) is an acridine derivative formerly widely used as an antimalarial. It is used in cell biological experiments as an inhibitor of phospholipase A2. purity: 100%
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Medchemexpress LLC HY-D0993 10mg Medchemexpress, Acridine Orange 10-Nonyl Bromide CAS:75168-11-5 Purity:>98%
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Medchemexpress, HY-D0993 10mg Acridine Orange 10-Nonyl Bromide CAS:75168-11-5 Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin (λ ex : 489 nm, λ em : 525 nm). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Acriflavine hydrochloride | 8063-24-9 | MFCD00069039 | 25G
Acriflavine hydrochloride | 8063-24-9 | MFCD00069039 | 25G
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Apexbio Technology LLC Acridine Orange Staining Kit 500T
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Acridine Orange Staining Kit is a fluorescence-based nucleic acid detection reagent designed for distinguishing cellular DNA and RNA particularly in apoptosis assays Acridine Orange is a cell membrane-permeant dye that selectively binds to double-stranded DNA emitting green fluorescence and to RNA or single-stranded DNA emitting orange or red fluorescence It is frequently used in combination with cell-impermeable dyes such as Ethidium Bromide or Propidium Iodide to differentiate viable apoptotic and necrotic cells according to selective membrane permeability and nuclear morphology changes during apoptosis Based on these properties Acridine Orange Staining Kit holds research potential in apoptosis detection and cell viability analysis
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Medchemexpress LLC Acridine orange (hydrochloride) | 65-61-2 | MFCD00150070 | 99.7% | 301.81 g/mol | C17H20ClN3 | 1 ML
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Acridine Orange hydrochloride is a cell-permeable, nucleic acid-selective fluorescent dye used to differentially stain DNA and RNA. In solution it emits green fluorescence when bound to double-stranded DNA (~530 nm) and orange/red fluorescence when bound to single-stranded DNA or RNA (~640 nm). Commonly supplied as a 10 mM solution in DMSO for laboratory research use.
- Cell-permeable nucleic acid-selective fluorescent dye.
- Distinguishes double-stranded DNA (green) from single-stranded DNA/RNA (orange/red).
- Available as a 10 mM solution in DMSO (1 mL) or as a solid form.
- Suitable for fluorescence microscopy and flow cytometry applications.
- Molecular formula C17H20ClN3; molecular weight 301.81 g/mol.
- For research use only; not for human or clinical use.
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Sigma Aldrich Fine Chemicals Biosciences Quinacrine dihydrochloride >=90% | 69-05-6 | MFCD00012659 | 100G
Quinacrine dihydrochloride >=90% | Purity: >=90% | Mol Wt: 472.88 | 69-05-6 | MFCD00012659 | 100G
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Sigma Aldrich Fine Chemicals Biosciences Acridine Mutagen ICR 191 | 17070-45-0 | MFCD00013320 | 10MG
Acridine Mutagen ICR 191 | Mol Wt: 451.22 | 17070-45-0 | MFCD00013320 | 10MG
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Apexbio Technology LLC Q-VD-OPh 1135695-98-5 25mg
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Q-VD-OPh is a pan-caspase inhibitor targeting caspases including 1 3 8 and 9 with IC50 values ranging from approximately 25 to 400 nM By blocking multiple caspase-mediated apoptotic pathways including caspase-9/3 caspase-8/10 and caspase-12 pathways Q-VD-OPh prevents apoptotic cell death induced by agents such as actinomycin D In research contexts this inhibitor serves as a tool to investigate apoptosis mechanisms across diverse cell types and species including human mouse and rat It is also used to enhance cell viability upon thawing from cryopreservation under standard cryoprotectant conditions
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Medchemexpress LLC 7PPD-Q | 2894124-00-4 | 98.9% | 312.41 | 5 MG
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7PPD-Q is a substituted p-phenylenediamine antioxidants derivative. It has been observed to be toxic to the bacterium V. fischeri (EC50 = 14.9 mg/L).
- For research use only.
- Not sold to patients.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428812 Q AGAROSE HP 100ML
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431380 Q AGAROSE 6FF 50ML
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Medchemexpress LLC 3,5-Dicaffeoyl-epi-quinic acid | 879305-14-3 | 97.7% | 516.45 | 5 MG
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3,5-Dicaffeoyl-epi-quinic acid is a compound extracted from *Chrysanthemum morifolium*. It demonstrates significant antioxidant activities, effectively scavenging DPPH radical and superoxide anion radical with IC50s of 5.6 and 2.9 μg/mL, respectively.
- Extracted from Chrysanthemum morifolium
- Exhibits antioxidant activities
- Scavenges DPPH radical and superoxide anion radical
- IC50s of 5.6 and 2.9 μg/mL for DPPH and superoxide anion radicals
- Appears as a white to off-white solid
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Medchemexpress LLC Hro761 2869954-34-5 98 5G | HY-148699-5G
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Hro761 2869954-34-5 98 5G
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